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13. Mutant Epidermal Growth Factor Receptor Up-Regulates Molecular Effectors of Tumor Invasion -- Lal et al. 62 (12): 3335 -- Cancer Research
- cancerres.aacrjournals.org
- Mutant Epidermal Growth Factor Receptor Up-Regulates Molecular Effectors of Tumor Invasion1 .
- Furthermore, inhibitors of EGFR (OSI-774 and Tyrphostin AG1478) selectively down-regulated these molecular effectors in glioblastoma cells, eliminating enhanced invasion. ...
- In conclusion, EGFRvIII induces a specific pattern of genes, and many of these genes are likely effectors of tumor invasion. ...
14. Environmental factors as regulators and effectors of multistep carcinogenesis -- Minamoto et al. 20 (4): 519 -- Carcinogenesis
- carcin.oupjournals.org
- Environmental factors as regulators and effectors of multistep carcinogenesis .
- effectors) for environmental factors include cellular regulatory proteins, which are essential for control of cell growth, DNA repair and programmed cell death. ...
- Within the cytosol, UV irradiation has been implicated in the activation of various signaling cascades including protein kinase C (PKC) (36), mitogen activated protein kinase (MAPK) (37), and JNK (38) with changes in downstream effectors, as shown for transcription factors cyclic AMP-response element binding protein (CREB) (39), jun (40), fos (41), p53 (42) and NFB (43). ...
15. Formins: signaling effectors for assembly and polarization of actin filaments -- Evangelista et al. 116 (13): 2603 -- Journal of Cell Science
- jcs.biologists.org
- Formins: signaling effectors for assembly and polarization of actin filaments .
16. The target of rapamycin (TOR) proteins -- Raught et al. 98 (13): 7037 -- Proceedings of the National Academy of Sciences
- www.pnas.org
- How does TOR signal to downstream effectors? TOR signaling is thought to be effected through a combination of direct phosphorylation of downstream targets, and repression of phosphatase activity (Fig. ...
- Phosphatases have been implicated in the dephosphorylation of several translation effectors, but are not depicted in this figure. ...
- Tor signals to several specific effectors (Tap42, Mks1p, Ure2p, Gln3p, and Gat1p) to elicit changes in the expression levels of enzymes involved in several different metabolic pathways (104, 105). ...
- Human Cytomegalovirus Infection Induces Rapamycin-Insensitive Phosphorylation of Downstream Effectors of mTOR Kinase.
17. Hyaluronan . Is Bigger Better? -- Camenisch and McDonald 23 (4): 431 -- American Journal of Respiratory Cell and Molecular Biology
- www.ajrcmb.org
- Ras, protein kinase C zeta, and I kappa B kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-kappa B by hyaluronic acid fragments in T-24 carcinoma cells. ...
18. the nervous system
- www.emc.maricopa.edu
- motor (efferent) pathways that carry signals to muscles and glands (effectors). ...
- Muscle fibers and gland cells are effectors. ...
19. Maintenance of muscle mass is not dependent on the calcineurin-NFAT pathway -- Dupont-Versteegden et al. 282 (6): C1387 -- AJP - Cell Physiology
- ajpcell.physiology.org
- Because calcineurin abundance was increased with atrophy in both models, we next examined downstream effectors in the calcineurin pathway: NFATc1 and MEF2C. ...
- Matching of calcineurin activity to upstream effectors is critical for skeletal muscle fiber growth. ...
20. Matrix metalloproteinases: effectors of development and normal physiology -- Vu and Werb 14 (17): 2123 -- Genes and Development
- www.genesdev.org
- Matrix metalloproteinases: effectors of development and normal physiology .
- The range of developmental effects seen in these function perturbation studies suggests that these enzymes do indeed participate as essential effectors of developmental processes in vivo. ...
21. Regulation of translation initiation by FRAP/mTOR -- Gingras et al. 15 (7): 807 -- Genes and Development
- www.genesdev.org
- Translational effectors are depicted in red. ...
- FRAP/mTOR signals to translation initiation effectors .
- eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation. ...
22. Detection and mutation of a luxS-encoded autoinducer in Proteus mirabilis -- Schneider et al. 148 (3): 773 -- Microbiology
- mic.sgmjournals.org
- Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. ...
23. Regulation of leukocyte recruitment by polypeptides derived from high molecular weight kininogen -- CHAVAKIS et al. 15 (13): 2365 -- The FASEB Journal
- www.fasebj.org
- (1988) The elevated natural killer sensitivity of targets carrying surface-attached C3 fragments require the availability of the iC3b receptor (CR3) on the effectors. ...
24. Pro- and macroglycogenolysis: relationship with exercise intensity and duration -- Graham et al. 90 (3): 873 -- Journal of Applied Physiology
- www.jap.org
- Glycogen phosphorylase: control by phosphorylation and allosteric effectors. ...
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