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• Direct comparisons of efficacy of this compounded product with commercially available clobetasol products are not available. ... 13 Increased efficacy by compounding with DermaZinc will be difficult to show. ...
• Efficacy is dependent on compliance .
• In the original studies designed to demonstrate efficacy, the drug was used as monotherapy with twice daily dosing, and demonstrated similar efficacy to fluocinonide ointment. ...
• Limited efficacy and high potential for irritation when used as a monotherapy .
• Patients must be told of the potential for irritation, and tazarotene should probably only be used in combination with Class I or II topical corticosteroids both to improve efficacy and to help minimize the potential for irritation. ...
• It is not yet known whether its penetration and efficacy in psoriasis would be aided by concomitant use of salicylic acid or other keratolytics. ...
• Efficacy may be increased by day treatment regimens or combination with low-dose acitretin. ...
• Combination with low dose acitretin improves efficacy and may reduce long-term side effects .
• Acitretin improves the efficacy of PUVA, helping to reduce the number of treatments needed (and hopefully, therefore, the long-term risk of carcinogenesis). ...
• Low dose therapy (25mg/day or 25mg every other day) is well tolerated and is usually sufficient to improve the efficacy of phototherapy. ...
• Acitretin is a very helpful adjunct for improving the efficacy of phototherapy. ...
• 12%: a novel vehicle with enhanced delivery and efficacy. ...
• Tazarotene gel, a new retinoid, for topical therapy of psoriasis: vehicle-controlled study of safety, efficacy, and duration of therapeutic effect. ...
• The safety and efficacy of tazarotene gel, a topical acetylenic retinoid, in the treatment of psoriasis. ...

• Lazaroids: efficacy and mechanism of action of the 21-aminosteroids in neuroprotection .
• The realization that the efficacy of methylprednisolone in reducing secondary injury was separate from its hormonal activity stimulated the development of a group of steroid analogues, the lazaroids (21-aminosteroids), that specifically inhibited lipid peroxidation without glucocorticoid or mineralocorticoid activity, thereby avoiding the complications of corticosteroid therapy. ...
• In head injury, the therapeutic efficacy of the lazaroids has been focussed on their role on membrane damage resulting from free radical reactions and the disruption in cellular ionic homeostasis, with less attention to other pathophysiological mechanisms such as release of excitotoxic amino acids. ...
• In a randomized, double-blind multi-centre trial11 investigating the efficacy of tirilazad in spinal cord injury, 499 patients with spinal cord injury diagnosed within 8 h of injury were randomized into three groups. ... It was postulated that the reduced efficacy of tirilazad compared with methylprednisolone might be due to a suboptimal dosage. ...
• The efficacy of tirilazad in cardiac arrest and resuscitation has been examined in animal models of global cerebral ischaemia and reperfusion. ...
• Clinical studies looking at the cerebroprotective efficacy of tirilazad in cerebral ischaemia have been disappointing. ...
• However, the evidence of the efficacy of tirilazad from phase III clinical trials is far from conclusive. ...
• The poor penetration of the blood–brain barrier of the lazaroids and its localization in the vascular membrane may significantly limit their efficacy. ... However, in the clinical studies looking at spinal cord injury11 and stroke,65 approximately half the patients received their first dose of tirilazad more than 3 h post-injury, and this could contribute to the apparent lack of clinical efficacy. ...
• However, the lack of efficacy of tirilazad in a number of clinical studies may have resulted from weaknesses within those studies. ...
• In the two large studies looking at the efficacy of tirilazad in the treatment of subarachnoid haemorrhage, one European, Australian and New Zealand study46 has shown a marked improvement in outcome for men, whereas a second North American study25 showed no difference in outcome. ...
• However, further studies using larger doses of tirilazad may show significant efficacy. ...
• Therapeutic efficacy of tirilazad in experimental multiple cerebral emboli. ...
• Neuroprotective efficacy of microvascularily-localized versus brain penetrating antioxidants. ...
• Efficacy of the 21-aminosteroid U-74006F in improving neurological recovery after spinal cord injury in rats. ...

• on the Power and Efficacy of Indulgences.
• on the Power and Efficacy of Indulgences.
• "Since the pope, by his pardons, seeks the salvation of souls rather than money, why does he suspend the indulgences and pardons granted heretofore, since these have equal efficacy?".

•    Home       About Us       Forums       Search       Feedback        Apologetics Bible Church History Miscellaneous Sacraments Soteriology Sermons For a Time Such as This The Obedience of Faith Worship Links <Print-Ready> Theologia Template >> Theologia :: Sacraments :: Baptismal Efficacy & the Reformed Tradition: Past, Present, & Future .
• BAPTISMAL EFFICACY AND.
• The earliest Reformers held a robust view of baptismal efficacy. ...
• Wright 6 summarizes: "What then about the efficacy of baptism according to the Westminster Confession? Its central affirmation seems clear: 'the grace promised is not only offered, but really exhibited and conferred by the Holy Ghost' (28. ... Most Presbyterians today focus on the qualifiers on baptismal efficacy in the Confession, rather than its central affirmation. ... While it would be going too far to say the Confession necessitates belief in baptismal regeneration, there can be no question such a view of baptismal efficacy is included in its parameters, if determined by original authorial intent 8 .
• But among the various positions of baptismal efficacy floating around, at least two noteworthy theologians held to forms of baptismal regeneration/justification. ...
• What does the Bible actually teach about the efficacy of baptism? While we cannot take the time and space here to do a thorough exegesis of all the references to baptism in the New Testament (much less the Old Testament), we can point to the face value meaning of several key passages. ...
• Of course, the ultimate proof of baptism's efficacy rests in the baptism of Jesus himself. ...
• Another escape route some Reformed theologians seek to take, in their flight from sacramental efficacy, is to claim these rituals are mere pictures 26 . ...
• In popular Reformed sacramental theology, this model is used to evacuate the sacraments of their efficacy. ... " But this notion of "sign" = "picture" needs to be challenged, along with the denigration of baptismal efficacy that it entails. ...
• To illustrate, consider what happens when a baptized person apostatizes (what we might call the "negative" efficacy of baptism). ...
• But this doesn't empty baptism of its efficacy. ... " None of the NT baptismal texts we have surveyed even hint that the rite is simply an ineffectual picture or symbol, nor do they give the impression that the efficacy attributed to baptism may takes place before or after the administration of the rite itself. ...
• It is impossible to summarize in brief form the richness of Leithart's approach, but we shall let him sketch the trajectory on which he is moving in his own words: "Questions concerning the efficacy of baptism have long divided Christians. Many Protestants fear that talk of 'baptismal regeneration' imputes an almost magical power to water, while Catholics and Orthodox accuse Protestants of robbing baptism of any efficacy at all. ...

• Efficacy of MRI and Mammography for Breast-Cancer Screening in Women with a Familial or Genetic Predisposition.
• Efficacy of MRI and Mammography for Breast-Cancer Screening in Women with a Familial or Genetic Predisposition .
• We compared the efficacy of magnetic resonance imaging (MRI) with that of mammography for screening in this group of high-risk women. ...

• Apical tuft input efficacy in layer 5 pyramidal cells from rat visual cortex.
• The special efficacy of tuft input arose because its electrotonic characteristics favour development of a sustained depolarization which charged the apex of the apical trunk to its firing threshold; once initiated in the distal trunk, firing propagated inward to the soma. ...
• Rather than disconnect the tuft, background synaptic conductance enhanced the efficacy advantage enjoyed by input arriving there. ...
• The advantage in efficacy was not dependent upon the characteristics of tuft membrane excitability, but rather stemmed from the geometry of the tuft and its junction with the distal apical trunk. The efficacy of tuft input was, however, critically dependent upon inward propagation, suggesting that modulation of membrane currents which affect propagation in the apical trunk might sensitively control the efficacy of tuft input. ...
• 1968, 1975)? In particular, how does the efficacy of synaptic input depend upon its spatial location and temporal pattern? The efficacy of a given synaptic input can clearly be altered by the non-linear responses of active membrane currents distributed in the dendritic tree, and so intuition derived from passive cable theory may not be a reliable guide. ...
• Vogt, 1991) because in passive dendritic models the efficacy of this distal synaptic input, which may arrive 1000 µm from the somata of layer 5 pyramidal cells, is small (e. ...
• To examine the efficacy of inputs to the apical tuft of layer 5 cortical pyramidal cells and compare it to that of more proximal apical input we employed compartment model simulations (Rall, 1964). ...
• Much of the available data on single neuron properties and on the efficacy of synaptic inputs have necessarily been collected in slices of cortex, in which spontaneous activity and hence synaptic input to the measured cells is low. ...
• Accordingly, in attempting to usefully characterize the efficacy of inputs to the layer 5 pyramidal cell apical dendrite, one wishes to utilize patterns of synaptic stimuli with some physiological relevance. ... The efficacy of this synaptic input was assessed over a 150 ms stimulation period comprising five input barrages. ...
• In the following, 30 Hz trains of synaptic input were used, and efficacy quantified as the somatic firing rate during a 150 ms period of input barrages. ...
• During this Ca2+ recovery period we found that the efficacy of further synaptic input to the apical dendrite was suppressed by dendritic Ca2+-gated K+ currents. ...
• Increased Ca2+ channel density in the apical dendrite decreased threshold level of input to the tuft adequate to trigger somatic firing to just 15 nS; thus the efficacy advantage enjoyed by synaptic input to the tuft remained. ...
• We re-examined the efficacy of apical tuft input when applied while the background was present. ...
• In contrast to the unimpaired efficacy of tuft input, the background markedly dampened the effect of proximal input to the apical oblique dendritic branches. ...

• Efficacy of Chest CT in a Pediatric ICU* .
• 2 The utility and efficacy of the portable CXR on the ICU have been extensively studied. ...
• To our knowledge, there are no published data on the indications for and efficacy of chest CT in the pediatric ICU (PICU) population. ...
• Several studies have examined the efficacy of chest CT in adult ICU patients,13 14 15 16 17 18 some of which have attempted to quantify the impact of CT on clinical management. ... 18 To our knowledge, ours is the first study to examine the efficacy of chest CT in PICU patients and the first to be performed prospectively. ...
• Bekemeyer, WB, Crapo, RO, Calhoon, S, et al (1985) Efficacy of chest radiography in a respiratory intensive care unit: a prospective study. ...
• Janower, ML, Jennas-Nocera, Z, Mukai, J (1984) Utility and efficacy of portable chest radiography. ...
• Henschke, CI, Pasternak, GS, Schroeder, S, et al (1983) Bedside chest radiography: diagnostic efficacy. ...
• Sivit, CJ, Taylor, GA, Hauser, GJ, et al (1989) Efficacy of chest radiography in pediatric intensive care. ...
• Henschke, CI, Yankelevitz, DF, Wand, A, et al (1996) Accuracy and efficacy of chest radiography in the intensive care unit. ...

• Efficacy and safety of antidepressants for children and adolescents.

• The Clinical Efficacy of Magnetic Resonance Imaging in Neuroimaging .
• Purpose: To assess the clinical efficacy of magnetic resonance imaging (MRI) for neuroimaging and to provide guidelines for clinical practice. ...

• Clinical efficacy of ketolides in the treatment of respiratory tract infections .

• Efficacy and Safety of Low-Carbohydrate Diets .
• Context  Low-carbohydrate diets have been popularized without detailed evidence of their efficacy or safety. ...

• Efficacy and Safety of Inhaled Corticosteroids .
• In a supplement to this journal published 5 yr ago the currently available data on efficacy and safety of inhaled corticosteroids was reviewed (2). Since then there have been many important developments in our understanding about how inhaled corticosteroids work in asthma, and much more data on the efficacy and safety of inhaled corticosteroids have been published. ...
•   CLINICAL EFFICACY OF INHALED CORTICOSTEROIDS .
• The clinical efficacy of inhaled corticosteroids in the treatment of asthma has been further established through the research produced during the last few years. ...
• Once again, however, no significant differences were seen between the effects of the different doses of FP (although there was a nonsignificant trend toward greater efficacy of the higher doses in two of the three studies). ...
• Two studies have indicated a greater efficacy for BUD Turbuhaler than for BDP pMDI (182, 183). ... The second study (183) suggested that BUD Turbuhaler 600 µg/d is equivalent in efficacy to BDP 1,000 µg/d. ...
• Finally, results from an open crossover study suggested a greater efficacy for 400 µg/d BUD Turbuhaler than for 400 µg/d BDP Rotahaler (187). ...
• A flat dose-response curve of lung function was seen, with no statistically significant differences in clinical efficacy between any dose of FP compared with the single dose of BDP, nor between the various doses of FP. ...
• One 3-mo study comparing nearly equal doses of BDP (1,600 µg/d) and FP (2,000 µg/d), both delivered by pMDI, showed that the two were similar in improving the efficacy of asthma control when prescribed to 134 patients who had previously received a lower dose of inhaled corticosteroid (190). ...
• A recent double-blind study compared the efficacy of BUD Turbuhaler and FP Diskhaler in 217 children with moderate asthma (180). ...
• There were no differences between the two drugs in the other measured efficacy markers, including day and nighttime asthma scores and rescue bronchodilator use. ...
• As seen with the comparisons of other drugs, it is impossible to draw unequivocal conclusions about the comparative efficacy of FP and BUD based on the studies published to date. ...
• Although a substantial number of comparative studies have been performed, it is difficult to draw firm conclusions about the comparative efficacy of different inhaled corticosteroids. ...
• Clinical Efficacy in Adults .

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